HMGB3 Antibody, Biotin conjugated

1. HMGB3 is involved in malignant transformation of hepatocytes and could be a useful biomarker for diagnosis and a potential target for therapy of liver cancer. PMID: 30166860
2. The study strongly suggests that HMGB3 promotes GBM oncogenesis through the MAPK signalling pathway while miR-200b-3p and miR-200c-3p inhibit its expression. PMID: 30232806
3. Luciferase reporter assays showed that HMGB3 was directly regulated by miR-205-5p in prostate cancer cells. PMID: 29196733
4. HMGB3 regulates the genes expression of WNT/beta-catenin pathway PMID: 28678825
5. Therefore, we infer that HMGB3 is a functional target of miR-27b in modulation of tamoxifen resistance and EMT. PMID: 27363334
6. these findings demonstrate that HMBG3 may be a potential molecular marker for predicting the prognosis of esophageal squamous cell carcinoma patients PMID: 25755721
7. our data suggests HMGB3 may serve as an important oncoprotein and indicate that overexpression of HMGB3 in urinary bladder cancer could be used as a potential prognostic marker. PMID: 25647262
8. High expression of HMGB3 is associated with lymph node metastases in gastric cancer. PMID: 25095979
9. In this family, microphthalmia, microcephaly, intellectual disability, and short stature are associated with a mutation on the X chromosome in the HMGB3 gene. PMID: 24993872
10. regulation of HMGB3 by miR-205 reduced both proliferation and invasion of breast cancer cells. PMID: 24098490
11. Association between co-expression networks involving HMGB3 and differentially-expressed genes in gastric cancer. PMID: 24338397
12. HMGB3 has a role in gastric cancer disease onset and progression by regulating the cell cycle PMID: 23326140
13. HMGB3 plays an important role in non-small cell lung cancer progression. PMID: 23609034
14. Data indicate that myomiR-206 modulates Hmgb3 expression during myogenesis. PMID: 22912879

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HGNC: 5004

OMIM: 300193

KEGG: hsa:3149

STRING: 9606.ENSP00000359393

UniGene: Hs.19114