HSD17B13 Antibody

Code CSB-PA907912
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA907912(HSD17B13 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA907912(HSD17B13 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
HSD17B13
Alternative Names
HSD17B13 antibody; SCDR9 antibody; SDR16C3 antibody; HMFN0376 antibody; UNQ497/PRO1014 antibody; 17-beta-hydroxysteroid dehydrogenase 13 antibody; 17-beta-HSD 13 antibody; EC 1.1.-.- antibody; Short chain dehydrogenase/reductase family 16C member 3 antibody; Short-chain dehydrogenase/reductase 9 antibody
Raised in
Rabbit
Species Reactivity
Human,Rat
Immunogen
Fusion protein of Human HSD17B13
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Lower HSD17B13 in peritumoral tissues was associated with worse recurrence free survival and overall survival of hepatocellular carcinoma patients and altered G1/S progression of HCC cells. PMID: 29748147
  2. We conducted a test for association between the rs72613567:TA variant and protection against severe liver fibrosis in 88 patients of Caucasian descent with HCV monoinfection. We conclude that rs72613567:TA is correlated with protection against liver fibrosis associated with HCV infection. PMID: 30403944
  3. A loss-of-function variant in HSD17B13 was associated with a reduced risk of chronic liver disease and of progression from steatosis to steatohepatitis. PMID: 29562163
  4. 17beta-HSD13 as a pathogenic protein in the development of nonalcoholic fatty liver disease. PMID: 25028495
  5. A new human short-chain dehydrogenase/reductase gene SCDR9 is cloned and expressed. PMID: 17311113

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Subcellular Location
Endoplasmic reticulum. Lipid droplet.
Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Tissue Specificity
Highly expressed in the liver. Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis.
Database Links

HGNC: 18685

OMIM: 612127

KEGG: hsa:345275

STRING: 9606.ENSP00000333300

UniGene: Hs.284414

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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