IFIT5 Antibody

Code CSB-PA011023LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot
    All lanes: IFIT5 antibody at 2µg/ml
    Lane 1: A375 whole cell lysate
    Lane 2: Jurkat whole cell lysate
    Lane 3: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 56, 51 kDa
    Observed band size: 56 kDa

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA011023LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA011023LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) IFIT5 Polyclonal antibody
Uniprot No. Q13325
Target Names IFIT5
Alternative Names FLJ53857 antibody; FLJ92678 antibody; IFIT-5 antibody; IFIT5 antibody; IFIT5_HUMAN antibody; Interferon induced protein with tetratricopeptide repeats 5 antibody; Interferon-induced protein with tetratricopeptide repeats 5 antibody; Retinoic acid and interferon inducible 58 kDa protein antibody; Retinoic acid and interferon inducible protein (58kD) antibody; Retinoic acid- and interferon-inducible 58 kDa protein antibody; RI58 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Interferon-induced protein with tetratricopeptide repeats 5 protein (107-320AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Interferon-induced RNA-binding protein involved in the human innate immune response. Has a broad and adaptable RNA structure recognition important for RNA recognition specificity in antiviral defense. Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments
Gene References into Functions
  1. IFIT5 promotes SeV-induced IKK phosphorylation and NF-kappaB activation by regulating the recruitment of IKK to TAK1. PMID: 26334375
  2. show that IFIT5 binds precursor and processed tRNAs, as well as other RNA polymerase III transcripts. Our findings establish the RNA recognition specificity of the human innate immune response protein IFIT5 PMID: 25092312
  3. TRIF-N-terminal helical domain shares structural similarity with IFIT5. PMID: 24311583
  4. IFIT5 consists of 24 alpha-helices that pack into a special "V"-like structure. PMID: 23774268
  5. IFIT5 recognizes cellular RNA instead of protein partners. PMID: 23317505
  6. crystal structures of human IFIT5, its complex with PPP-RNAs, and an amino-terminal fragment of IFIT1 PMID: 23334420

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Subcellular Location Cell projection, ruffle membrane
Protein Families IFIT family
Database Links

HGNC: 13328

OMIM: 616135

KEGG: hsa:24138

STRING: 9606.ENSP00000360860

UniGene: Hs.252839

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