IL17D Antibody

Code CSB-PA157805
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA157805(IL17D Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA157805(IL17D Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
Alternative Names
IL 17D antibody; IL 22 antibody; IL 27 antibody; IL-17D antibody; IL-27 antibody; IL17D antibody; IL17D_HUMAN antibody; IL27 antibody; Interleukin 17D antibody; Interleukin 27 antibody; Interleukin-17D antibody; Interleukin-27 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human IL17D
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.
Gene References into Functions
  1. Nrf2 Induces IL-17D to mediate tumor and virus surveillance. PMID: 27545889
  2. Study of the expression of IL-17 provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor. PMID: 28685546
  3. Utilizing gene microarray analysis, authors found the cytokine interleukin 17D (IL-17D) was highly expressed in certain unedited tumors. PMID: 24794441
  4. These experiments were designed to investigate the effects of IL-17 upon the phenotype and function of human Natural Killer (NK) cells. PMID: 23490420
  5. IL-27 priming results in enhanced lipopolysaccharide-induced IL-6, tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta expression in human primary monocytes. PMID: 22156348
  6. IL-17D stimulates production of cytokines in endothelial cells in vitro and suppresses proliferation of myeloid progenitors in colony formation assays. PMID: 12097364

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Subcellular Location
Secreted.
Protein Families
IL-17 family
Tissue Specificity
Expressed preferentially in adipose, skeletal muscle and CNS.
Database Links

HGNC: 5984

OMIM: 607587

KEGG: hsa:53342

STRING: 9606.ENSP00000302924

UniGene: Hs.655142

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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