IL17D Antibody, FITC conjugated

Code CSB-PA848386LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) IL17D Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
IL 17D antibody; IL 22 antibody; IL 27 antibody; IL-17D antibody; IL-27 antibody; IL17D antibody; IL17D_HUMAN antibody; IL27 antibody; Interleukin 17D antibody; Interleukin 27 antibody; Interleukin-17D antibody; Interleukin-27 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Interleukin-17D protein (16-202AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.
Gene References into Functions
  1. Nrf2 Induces IL-17D to mediate tumor and virus surveillance. PMID: 27545889
  2. Study of the expression of IL-17 provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor. PMID: 28685546
  3. Utilizing gene microarray analysis, authors found the cytokine interleukin 17D (IL-17D) was highly expressed in certain unedited tumors. PMID: 24794441
  4. These experiments were designed to investigate the effects of IL-17 upon the phenotype and function of human Natural Killer (NK) cells. PMID: 23490420
  5. IL-27 priming results in enhanced lipopolysaccharide-induced IL-6, tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta expression in human primary monocytes. PMID: 22156348
  6. IL-17D stimulates production of cytokines in endothelial cells in vitro and suppresses proliferation of myeloid progenitors in colony formation assays. PMID: 12097364

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Subcellular Location
Secreted.
Protein Families
IL-17 family
Tissue Specificity
Expressed preferentially in adipose, skeletal muscle and CNS.
Database Links

HGNC: 5984

OMIM: 607587

KEGG: hsa:53342

STRING: 9606.ENSP00000302924

UniGene: Hs.655142

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