IL17D Antibody

Datasheet

Code	CSB-PA141453
Size	US$119
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Image	Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100 Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100 Immunohistochemical analysis of paraffin-embedded Human-brain, antibody was diluted at 1:100
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Product Details
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Target Background

Product Details

Uniprot No.

Q8TAD2

Target Names

IL17D

Alternative Names

IL 17D antibody; IL 22 antibody; IL 27 antibody; IL-17D antibody; IL-27 antibody; IL17D antibody; IL17D_HUMAN antibody; IL27 antibody; Interleukin 17D antibody; Interleukin 27 antibody; Interleukin-17D antibody; Interleukin-27 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide from Human protein at AA range: 141-190

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Purification Method

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

IHC,ELISA

Recommended Dilution

Application	Recommended Dilution
IHC	1:50-300
ELISA	1:10000-20000

Protocols

Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.

Gene References into Functions

Nrf2 Induces IL-17D to mediate tumor and virus surveillance. PMID: 27545889
Study of the expression of IL-17 provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor. PMID: 28685546
Utilizing gene microarray analysis, authors found the cytokine interleukin 17D (IL-17D) was highly expressed in certain unedited tumors. PMID: 24794441
These experiments were designed to investigate the effects of IL-17 upon the phenotype and function of human Natural Killer (NK) cells. PMID: 23490420
IL-27 priming results in enhanced lipopolysaccharide-induced IL-6, tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta expression in human primary monocytes. PMID: 22156348
IL-17D stimulates production of cytokines in endothelial cells in vitro and suppresses proliferation of myeloid progenitors in colony formation assays. PMID: 12097364

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Subcellular Location

Secreted.

Protein Families

IL-17 family

Tissue Specificity

Expressed preferentially in adipose, skeletal muscle and CNS.

Database Links

HGNC: 5984

OMIM: 607587

KEGG: hsa:53342

STRING: 9606.ENSP00000302924

UniGene: Hs.655142

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Related pathways

Jak-STAT signaling pathway IL-17 signaling pathway Th17 cell differentiation

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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