IL17D Antibody, Biotin conjugated

Code CSB-PA848386LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) IL17D Polyclonal antibody
Uniprot No.
Target Names
IL17D
Alternative Names
IL 17D antibody; IL 22 antibody; IL 27 antibody; IL-17D antibody; IL-27 antibody; IL17D antibody; IL17D_HUMAN antibody; IL27 antibody; Interleukin 17D antibody; Interleukin 27 antibody; Interleukin-17D antibody; Interleukin-27 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Interleukin-17D protein (16-202AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.
Gene References into Functions
  1. Nrf2 Induces IL-17D to mediate tumor and virus surveillance. PMID: 27545889
  2. Study of the expression of IL-17 provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor. PMID: 28685546
  3. Utilizing gene microarray analysis, authors found the cytokine interleukin 17D (IL-17D) was highly expressed in certain unedited tumors. PMID: 24794441
  4. These experiments were designed to investigate the effects of IL-17 upon the phenotype and function of human Natural Killer (NK) cells. PMID: 23490420
  5. IL-27 priming results in enhanced lipopolysaccharide-induced IL-6, tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta expression in human primary monocytes. PMID: 22156348
  6. IL-17D stimulates production of cytokines in endothelial cells in vitro and suppresses proliferation of myeloid progenitors in colony formation assays. PMID: 12097364

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Subcellular Location
Secreted.
Protein Families
IL-17 family
Tissue Specificity
Expressed preferentially in adipose, skeletal muscle and CNS.
Database Links

HGNC: 5984

OMIM: 607587

KEGG: hsa:53342

STRING: 9606.ENSP00000302924

UniGene: Hs.655142

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