IL17RE Antibody

Code CSB-PA011606GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
IL17RE
Alternative Names
IL17RE antibody; UNQ3056/PRO9877 antibody; Interleukin-17 receptor E antibody; IL-17 receptor E antibody; IL-17RE antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human IL17RE
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.
Gene References into Functions
  1. IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens. PMID: 21993849
Subcellular Location
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Secreted.; [Isoform 4]: Cytoplasm.; [Isoform 5]: Secreted.
Tissue Specificity
Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines.
Database Links

HGNC: 18439

OMIM: 614995

KEGG: hsa:132014

STRING: 9606.ENSP00000295980

UniGene: Hs.390823

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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