IL20RA Antibody

Code CSB-PA887035ESR1HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA887035ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA887035ESR1HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) IL20RA Polyclonal antibody
Uniprot No. Q9UHF4
Target Names IL20RA
Alternative Names class II cytokine receptor ZCYTOR7 antibody; CRF2 8 antibody; CRF2-8 antibody; Cytokine receptor class II member 8 antibody; Cytokine receptor class-II member 8 antibody; Cytokine receptor family 2 member 8 antibody; I20RA_HUMAN antibody; IL 20R alpha antibody; IL 20R1 antibody; IL-20 receptor subunit alpha antibody; IL-20R-alpha antibody; IL-20R1 antibody; IL-20RA antibody; IL20 Receptor alpha antibody; IL20RA antibody; Interleukin 20 receptor alpha chain antibody; Interleukin 20 receptor, alpha antibody; interleukin-20 receptor I antibody; Interleukin-20 receptor subunit alpha antibody; ZcytoR7 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Interleukin-20 receptor subunit alpha protein (30-250AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
Gene References into Functions
  1. the DNA fragment containing the associated SNPs interacts through chromatin looping not only with TNFAIP3, but also with IL20RA, located 680 kb upstream. PMID: 27799070
  2. IL20R1 correlated with prognosis of patients with pancreatic cancer, and mediates pancreatic cancer cell growth and migration. It may be a potential biomarker for IL24 molecular-targeted therapy. PMID: 26977011
  3. crystallographic asymmetric unit contains one IL-20-IL-20R1-IL-20R2 complex, corresponding to a solvent content of approximately 54% PMID: 22232181
  4. IL-20RA polymorphisms may have a role in psoriasis PMID: 19926456
  5. Complete mda-7/IL-24 receptors (IL-22R1/IL-20R2 and IL-20R1/IL-20R2) are seldom expressed in liver cancer cell lines. PMID: 19666410
  6. forms stable complex with interleukin-19 and interleukin-20 [IL-20R1][IL-20R2] PMID: 14580208
  7. sensitivity to recombinant interleukin-26(IL-26) of various cell lines strictly correlated with the expression of IL-20 1 receptor and blocking antibodies against either IL-10 receptor 2 or IL-20 receptor 1 inhibited IL-26-dependent signal transduction PMID: 15178681
  8. The hypotheses that genetic variations of the IL-20-RI influence susceptibility to psoriasis was investigated. PMID: 18480827

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Subcellular Location Membrane; Single-pass type I membrane protein.
Protein Families Type II cytokine receptor family
Tissue Specificity Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.
Database Links

HGNC: 6003

OMIM: 605620

KEGG: hsa:53832

STRING: 9606.ENSP00000314976

UniGene: Hs.445868

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