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ISCA2 Antibody, HRP conjugated

Datasheet
Code CSB-PA769773LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ISCA2 Polyclonal antibody
Uniprot No.
Q86U28
Target Names
ISCA2
Alternative Names
c14_5557 antibody; HESB like domain containing 1 antibody; HESB like domain containing protein 1 antibody; HESB-like domain-containing protein 1 antibody; iron sulfur cluster assembly 2 homolog (S. cerevisiae) antibody; Iron sulfur cluster assembly 2 homolog; mitochondrial antibody; Iron-sulfur cluster assembly 2 homolog; mitochondrial antibody; ISCA2 antibody; ISCA2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Iron-sulfur cluster assembly 2 homolog, mitochondrial protein (9-154AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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ISCA2 Antibodies

ISCA2 Proteins

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Target Background

Function
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.
Gene References into Functions
  1. We identified a homoallelic missense founder mutation in ISCA2 leading to mitochondrial depletion and reduced complex I activity as well as decreased ISCA2, ISCA1 and IBA57 expression in fibroblasts. PMID: 25539947
Involvement in disease
Multiple mitochondrial dysfunctions syndrome 4 (MMDS4)
Subcellular Location
Mitochondrion.
Protein Families
HesB/IscA family
Database Links

HGNC: 19857

OMIM: 615317

KEGG: hsa:122961

STRING: 9606.ENSP00000452007

UniGene: Hs.291079

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