Il18bp Antibody

Datasheet

Code	CSB-PA16769A0Rb
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA16769A0Rb at dilution of 1:20
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) Il18bp Polyclonal antibody

Uniprot No.

Q9Z0M9

Target Names

Il18bp

Alternative Names

Il18bp antibody; Igifbp antibody; Interleukin-18-binding protein antibody; IL-18BP antibody; Interferon gamma-inducing factor-binding protein antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse Interleukin-18-binding protein (29-193AA)

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

The Il18bp Antibody (Product code: CSB-PA16769A0Rb) is Non-conjugated. For Il18bp Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA16769B0Rb	Il18bp Antibody, HRP conjugated	ELISA
FITC	CSB-PA16769C0Rb	Il18bp Antibody, FITC conjugated
Biotin	CSB-PA16769D0Rb	Il18bp Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:10-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.

Gene References into Functions

IL-18BP ameliorates cardiac ischemia/reperfusion injury in part through suppression of Th17 differentiation. PMID: 26340315
Data show that IL-18bp acts as a sensor for IFN-gamma and can regulate both Th1 and Th17 responses in the CNS. PMID: 20644165
Administratioan of murine IL-18BP at the time of the booster injection of bovine CII reduces the progressive severity of collagen-induced arthritis; both clinical disease activity and histological scores are decreased by 50%. PMID: 12574381
functional polarization of Ag-specific CD4(+) Th2 cells entering the CNS during the accelerating phase of experimental autoimmune encephalomyelitis is flexible and dependent on IL-18, which is overturned by IL-18 binding protein PMID: 15778395
IL-18 and IL-18BP may have roles in testicular development, and also in the regulation of testicular functions under physiological conditions PMID: 18299271
A single intravenous dose of recombinant mouse IL18BP decreased neointimal hyperplasia and improved arterial L/A ratios in an atherosclerotic balloon-injury animal model. PMID: 18455646

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Subcellular Location

Secreted.

Database Links

KEGG: mmu:16068

STRING: 10090.ENSMUSP00000091685

UniGene: Mm.422756

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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