JPH1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA872553LD01HU
Size US$299
Uniprot No. Q9HDC5
Protocols ELISA Protocol
Immunogen Recombinant Human Junctophilin-1 protein (431-546AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Junctophilin-1 (JP-1) (Junctophilin type 1), JPH1, JP1
Immunogen Species Homo sapiens (Human)
Research Area Cell Biology
Target Names JPH1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
Subcellular Location Cell membrane, Peripheral membrane protein, Endoplasmic reticulum membrane, Single-pass type IV membrane protein, Sarcoplasmic reticulum membrane, Single-pass type IV membrane protein
Protein Families Junctophilin family
Tissue Specificity Abundantly expressed in skeletal muscle. Very low levels in heart.
Database Links

HGNC: 14201

OMIM: 605266

KEGG: hsa:56704

STRING: 9606.ENSP00000344488

UniGene: Hs.657367

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