JRK Antibody

Code CSB-PA525639NA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: SH-SY5Y whole cell lysate, Mouse heart tissue
    All lanes: JRK antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 62, 63 kDa
    Observed band size: 62 kDa
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) JRK Polyclonal antibody
Uniprot No.
Target Names
JRK
Alternative Names
JRK antibody; JH8 antibody; Jerky protein homolog antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Peptide sequence from Human Jerky protein homolog protein (465-483AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The JRK Antibody (Product code: CSB-PA525639NA01HU) is Non-conjugated. For JRK Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA525639NB01HU JRK Antibody, HRP conjugated ELISA
FITC CSB-PA525639NC01HU JRK Antibody, FITC conjugated
Biotin CSB-PA525639ND01HU JRK Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
May bind DNA.
Gene References into Functions
  1. JRK expression was aberrantly elevated in 21% of colorectal cancers, 15% of breast and ovarian cancers and was associated with increased expression of beta-catenin target genes and increased cell proliferation PMID: 26455321
  2. in the adult intestine, Ebd acts independently of Ewg in physiological Wnt signaling, but cooperates with Ewg to induce the hyperactivation of Wnt target gene expression following Apc1 loss. These findings have relevance for human tumorigenesis, as Jerky (JRK/JH8), the human Ebd homolog, promotes Wnt pathway hyperactivation and is overexpressed in colorectal, breast, and ovarian cancers PMID: 28708826
Subcellular Location
Nucleus.
Protein Families
Tigger transposable element derived protein family
Tissue Specificity
Expressed ubiquitously.
Database Links

HGNC: 6199

OMIM: 603210

KEGG: hsa:8629

UniGene: Hs.535903

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