KCNA10 Antibody

Code CSB-PA988090
Size US$119
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  • Western blot analysis of 1) Rat Brain Tissue, 2)Mouse Brain Tissue with KV1.8 Rabbit pAb diluted at 1:2,000.
  • Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using Kv1.8 Rabbit pAb diluted at 1:200.
  • Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using Kv1.8 Rabbit pAb diluted at 1:200.
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Product Details

Uniprot No.
Target Names
KCNA10
Alternative Names
KCNA10; Potassium voltage-gated channel subfamily A member 10; Voltage-gated potassium channel subunit Kv1.8
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic Peptide
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:1000-2000
IHC 1:100-200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP.
Gene References into Functions
  1. KCNA10 in human proximal tubular cells, glomerular and vascular endothelial cells, and also in vascular smooth muscle cells. PMID: 12444201
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Potassium channel family, A (Shaker) (TC 1.A.1.2) subfamily, Kv1.8/KCNA10 sub-subfamily
Tissue Specificity
Detected in kidney, in proximal tubules, glomerular endothelium, in vascular endothelium and in smooth muscle cells.
Database Links

HGNC: 6219

OMIM: 602420

KEGG: hsa:3744

STRING: 9606.ENSP00000358786

UniGene: Hs.248140

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