KCNA10 Antibody

Code CSB-PA988090
Size US$100
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  • Western blot analysis of 1) Rat Brain Tissue, 2)Mouse Brain Tissue with KV1.8 Rabbit pAb diluted at 1:2,000.
  • Immunohistochemical analysis of paraffin-embedded Rat BrainTissue using Kv1.8 Rabbit pAb diluted at 1:200.
  • Immunohistochemical analysis of paraffin-embedded Mouse BrainTissue using Kv1.8 Rabbit pAb diluted at 1:200.
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Product Details

Uniprot No.
Target Names
KCNA10
Alternative Names
KCNA10; Potassium voltage-gated channel subfamily A member 10; Voltage-gated potassium channel subunit Kv1.8
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic Peptide
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:1000-2000
IHC 1:100-200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP.
Gene References into Functions
  1. KCNA10 in human proximal tubular cells, glomerular and vascular endothelial cells, and also in vascular smooth muscle cells. PMID: 12444201
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Potassium channel family, A (Shaker) (TC 1.A.1.2) subfamily, Kv1.8/KCNA10 sub-subfamily
Tissue Specificity
Detected in kidney, in proximal tubules, glomerular endothelium, in vascular endothelium and in smooth muscle cells.
Database Links

HGNC: 6219

OMIM: 602420

KEGG: hsa:3744

STRING: 9606.ENSP00000358786

UniGene: Hs.248140

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