L3MBTL2 Antibody

Datasheet

Code	CSB-PA839279LA01HU
Size	$600
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Image	Positive WB detected in: Hela whole cell lysate(30µg), HepG2 whole cell lysate(30µg) All lanes: L3MBTL2 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/20000 dilution Predicted band size: 80,70 kDa Observed band size: 95-100 kDa Exposure time: 120s
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) L3MBTL2 Polyclonal antibody

Uniprot No.

Q969R5

Target Names

L3MBTL2

Alternative Names

3bt like 2 protein antibody; 3bt like protein antibody; DKFZP761I141 antibody; H-l(3)mbt-like protein 2 antibody; H-l(3)mbt-like protein antibody; Hl antibody; Hl(3)mbt like protein antibody; Hl(3)mbtl antibody; L antibody; l(3)mbt like 2 (Drosophila) antibody; l(3)mbt like 2 antibody; L(3)mbt-like 2 protein antibody; L(3)mbt-like protein 2 antibody; L3MBTL2 antibody; Lethal antibody; Lethal(3)malignant brain tumor-like 2 protein antibody; Lethal(3)malignant brain tumor-like protein 2 antibody; LMBL2_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Lethal(3)malignant brain tumor-like protein 2 protein

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

0.02% sodium azide
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

Gene References into Functions

L3MBTL2 polymorphism is associated with neuroticism. PMID: 27918536
Our findings highlight a PcG/L3MBTL2 collaboration that attains repressive chromatin without entailing histone lysine methylation marks. PMID: 21596310
High-resolution crystallographic analysis of the four MBT repeats of L3MBTL2 reveals its unique asymmetric rhomboid architecture, as well as binding mechanism, which preclude the interaction of the first three MBT repeats with methylated peptides. PMID: 19233876
determination of the solution structure of the FCS zinc finger of L3MBTL2; structure consists of a beta-hairpin followed by an alpha-helix; structure is consistent with the proposal that FCS zinc fingers bind to regulatory RNAs PMID: 19241375

Subcellular Location

Nucleus.

Database Links

HGNC: 18594

OMIM: 611865

KEGG: hsa:83746

STRING: 9606.ENSP00000216237

UniGene: Hs.517641

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Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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