LGALS12 Antibody

Code CSB-PA846606LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: A549 whole cell lysate, Rat kidney tissue
    All lanes: LGALS12 antibody at 3µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 38, 32, 37, 30, 36 kDa
    Observed band size: 38 kDa

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA846606LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA846606LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) LGALS12 Polyclonal antibody
Uniprot No.
Target Names
LGALS12
Alternative Names
Gal-12 antibody; Galectin related inhibitor of proliferation antibody; Galectin-12 antibody; Galectin-related inhibitor of proliferation antibody; GRIP1 antibody; Lectin galactoside binding soluble 12 (galectin 12) antibody; LEG12_HUMAN antibody; Lgals12 antibody
Raised in
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant Human Galectin-12 protein (1-336AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The LGALS12 Antibody (Product code: CSB-PA846606LA01HU) is Non-conjugated. For LGALS12 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA846606LB01HU LGALS12 Antibody, HRP conjugated ELISA
FITC CSB-PA846606LC01HU LGALS12 Antibody, FITC conjugated
Biotin CSB-PA846606LD01HU LGALS12 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description
LGALS12 polyclonal antibody CSB-PA846606LA01HU was produced in the rabbit immunized by using the Recombinant Human Galectin-12 protein (1-336AA) as the immunogen. The target protein LGALS12, a member of the galectin superfamily, a group of beta-galactoside-binding proteins with conserved carbohydrate recognition domains. It can bind lactose and May participate in the apoptosis of adipocytes. The related mouse protein is a primary regulator of the early stages of adipose tissue development.
This Rabbit anti-Homo sapiens (Human) LGALS12 Polyclonal antibody was tested in the ELISA, WB and IHC applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It reacts with the LGALS12 proteins of human or rat-origin and may be used to detect the endogenous levels of LGALS12 protein.

Customer Reviews and Q&A

 Customer Reviews
Average Rating:
5.0 - 1 reviews

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Applications : In vitro killing assay

Sample type: cells

Review: The specific lysis after coculture with U937CD33 cells at a 1:1 in the presence of recombinant galectin 12 protein (10 µg/ml) and galectin 12 antibody.

By Anonymous

Target Background

Function
Binds lactose. May participate in the apoptosis of adipocytes.
Gene References into Functions
  1. Galectin-12 is silenced in colorectal cancer via hypermethylation of its promoter. PMID: 29098769
  2. Overexpression of galectin-12 contributes to a differentiation block in acute promyelocytic leukemia cells, and suppression of galectin-12 facilitates granulocytic differentiation. PMID: 27256573
  3. Lower LGALS12 gene expression is associated with acute myeloid leukemia. PMID: 25953264
  4. results suggest that mouse galectin-12 is a major regulator of adipose tissue development PMID: 15131127
Subcellular Location
Nucleus.
Tissue Specificity
Not widely expressed. Predominantly expressed in adipose tissue.
Database Links

HGNC: 15788

OMIM: 606096

KEGG: hsa:85329

STRING: 9606.ENSP00000339374

UniGene: Hs.502774

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