LYPLAL1 Antibody

Datasheet

Code	CSB-PA736204LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA736204LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA736204LA01HU at dilution of 1:100 Immunofluorescent analysis of PC-3 cells using CSB-PA736204LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) LYPLAL1 Polyclonal antibody

Uniprot No.

Q5VWZ2

Target Names

LYPLAL1

Alternative Names

BC027340 antibody; FLJ99730 antibody; KIAA1238 antibody; LYPL1_HUMAN antibody; LYPLAL1 antibody; Lysophospholipase like 1 antibody; Lysophospholipase-like protein 1 antibody; MGC28394 antibody; OTTHUMP00000035229 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Lysophospholipase-like protein 1 protein (2-237AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The LYPLAL1 Antibody (Product code: CSB-PA736204LA01HU) is Non-conjugated. For LYPLAL1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA736204LB01HU	LYPLAL1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA736204LC01HU	LYPLAL1 Antibody, FITC conjugated
Biotin	CSB-PA736204LD01HU	LYPLAL1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site.

Gene References into Functions

Novel LYPLAL1 SNP rs2605100 is associated with childhood hypertension adjusted by obesity. PMID: 28645872
The LYPLAL1 genotype is associated with differences in eating behavior and loss of extensive body weight following Roux-en-Y gastric bypass (RYGB) surgery. Genotyping and the use of eating behavior-related questionnaires may help to estimate the RYGB-associated therapy success. PMID: 27181159
Data provide evidence that variants of MC4R and LYPLAL1 modulate body fat distribution with sexual dimorphism in a Chinese population. PMID: 26848030
Our results suggest that LYPLAL1 rs4846567 and NISCH rs6784615 may influence fat distribution in the Japanese population. PMID: 23221025
genetic association studies in Danish population: Quantitative metabolic phenotypes in obesity are associated with SNP in various genes: LYPLAL1 (rs4846567) is associated with waist-hip ratio and insulin sensitivity in women. PMID: 21953277
Gene-treatment interactions were observed for short-term weight loss. (LYPLAL1 rs2605100, Plifestyle*SNP = 0.032) PMID: 22179955
LYPLAL1 exhibits neither phospholipase nor triacylglycerol lipase activity, but rather accepts short-chain substrates PMID: 22052940
central obesity-associated variants in LYPLAL1, NRXN3, MSRA, and TFAP2B PMID: 21674055
TFAP2B, LYPLAL1 and MSRA are associated with adiposity and fat distribution. PMID: 19557161

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Subcellular Location

[Isoform 1]: Cytoplasm, cytosol.; [Isoform 2]: Cytoplasm, cytosol.

Protein Families

AB hydrolase superfamily, AB hydrolase 2 family

Database Links

HGNC: 20440

OMIM: 616548

KEGG: hsa:127018

STRING: 9606.ENSP00000355895

UniGene: Hs.657617

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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