MAGEA10 Antibody

Code CSB-PA216191
Size US$299
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA216191(MAGEA10 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A375 cells, Primary antibody: CSB-PA216191(MAGEA10 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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Product Details

Uniprot No. P43363
Target Names MAGEA10
Alternative Names MAGEA10 antibody; MAGE10Melanoma-associated antigen 10 antibody; Cancer/testis antigen 1.10 antibody; CT1.10 antibody; MAGE-10 antigen antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Fusion protein of Human MAGEA10
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method Antigen affinity purification
Concentration It differs from different batches. Please contact us to confirm it.
Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form Liquid
Tested Applications ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
WB 1:1000-1:5000
IHC 1:50-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Gene References into Functions
  1. By using Molecular-Docking, 3 MAGEA10 peptides were found binding to the groove position of HLA-A( *)0210 same as MAGEA4 peptide co-crystallized with HLA-A( *)0210, which indicates they could be promising for HLA-A( *)0201 presentation in immunotherapy. PMID: 26058806
  2. We clearly showed that MAGE-A10 is frequently expressed in the group of triple-negative breast cancer patients PMID: 22116775
  3. High MAGE-A10 is associated with lung, skin and urothelial malignancies. PMID: 21710496
  4. This is the first report of these MAGE-A10 alternative splice sequences, and characterization of MAGE-A expression PMID: 15355897
Subcellular Location Nucleus
Tissue Specificity Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for spermatogonia, spermatocytes and placenta.
Database Links

HGNC: 6797

OMIM: 300343

KEGG: hsa:4109

STRING: 9606.ENSP00000244096

UniGene: Hs.18048

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