MAP9 Antibody

Code CSB-PA060167
Size US$100
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Product Details

Uniprot No.
Target Names
MAP9
Alternative Names
ASAP antibody; Aster associated protein antibody; Aster-associated protein antibody; Map9 antibody; MAP9_HUMAN antibody; microtubule associated protein 9 antibody; Microtubule-associated protein 9 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human MAP-9.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.
Gene References into Functions
  1. MAP9 downregulation is associated with colorectal malignancy. PMID: 24876664
  2. ASAP stabilizes p53 both by alleviating MDM2-mediated p53 ubiquitination and by enhancing its p300-dependent acetylation. PMID: 22672907
  3. Results highlight dual ASAP regulation by Plk1 and further confirm the importance of ASAP for spindle pole organization, bipolar spindle assembly, and mitosis. PMID: 20615875
  4. ASAP is a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis. PMID: 16049101
  5. Study demonstrates that AurA-mediated phosphorylation of ASAP is essential to spindle formation and mitosis. PMID: 17925329

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Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
Database Links

HGNC: 26118

OMIM: 610070

KEGG: hsa:79884

STRING: 9606.ENSP00000310593

UniGene: Hs.61271

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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