MAP9 Antibody

Code CSB-PA102126
Size US$297
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  • Western blot analysis of extracts from HuvEc cell, using MAP9 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MAP9 Polyclonal antibody
Uniprot No.
Target Names
MAP9
Alternative Names
ASAP antibody; Aster associated protein antibody; Aster-associated protein antibody; Map9 antibody; MAP9_HUMAN antibody; microtubule associated protein 9 antibody; Microtubule-associated protein 9 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human MAP9.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.
Gene References into Functions
  1. MAP9 downregulation is associated with colorectal malignancy. PMID: 24876664
  2. ASAP stabilizes p53 both by alleviating MDM2-mediated p53 ubiquitination and by enhancing its p300-dependent acetylation. PMID: 22672907
  3. Results highlight dual ASAP regulation by Plk1 and further confirm the importance of ASAP for spindle pole organization, bipolar spindle assembly, and mitosis. PMID: 20615875
  4. ASAP is a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis. PMID: 16049101
  5. Study demonstrates that AurA-mediated phosphorylation of ASAP is essential to spindle formation and mitosis. PMID: 17925329

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Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
Database Links

HGNC: 26118

OMIM: 610070

KEGG: hsa:79884

STRING: 9606.ENSP00000310593

UniGene: Hs.61271

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