MAPK8IP2 Antibody

Code CSB-PA621663ESR2HU
Size US$166
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  • Western blot
    All lanes: MAPK8IP2 antibody at 2.85µg/ml
    Lane 1: U251 whole cell lysate
    Lane 2: A549 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 88, 85, 65, 50 kDa
    Observed band size: 88 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MAPK8IP2 Polyclonal antibody
Uniprot No.
Target Names
MAPK8IP2
Alternative Names
C jun amino terminal kinase interacting protein 2 antibody; C-jun-amino-terminal kinase-interacting protein 2 antibody; Homologous to mouse JIP 1 antibody; IB 2 antibody; IB-2 antibody; IB2 antibody; Islet brain 2 antibody; Islet-brain-2 antibody; JIP 2 antibody; JIP-2 antibody; JIP2 antibody; JIP2_HUMAN antibody; JNK interacting protein 2 antibody; JNK MAP kinase scaffold protein 2 antibody; JNK MAP kinase scaffold protein JIP2 antibody; JNK-interacting protein 2 antibody; MAPK8IP2 antibody; Mitogen activated protein kinase 8 interacting protein 2 antibody; Mitogen-activated protein kinase 8-interacting protein 2 antibody; PRKM8 interacting protein like antibody; PRKM8IPL antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human C-Jun-amino-terminal kinase-interacting protein 2 protein (470-570AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.
Gene References into Functions
  1. Human IB2 mutation has a role as a contributing genetic factor in chromosome 22-associated cognitive disorders. PMID: 21048139
  2. there is a signaling module in which IB2 scaffolds a MLK3/MKK/p38delta kinase cascade. PMID: 12244047
Subcellular Location
Cytoplasm.
Protein Families
JIP scaffold family
Tissue Specificity
Expressed mainly in the brain and pancreas, including insulin-secreting cells. In the nervous system, more abundantly expressed in the cerebellum, pituitary gland, occipital lobe and the amygdala. Also expressed in fetal brain. Very low levels found in ut
Database Links

HGNC: 6883

OMIM: 607755

KEGG: hsa:23542

STRING: 9606.ENSP00000330572

UniGene: Hs.558180

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