MARVELD3 Antibody, FITC conjugated

Code CSB-PA842633LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MARVELD3 Polyclonal antibody
Uniprot No.
Target Names
MARVELD3
Alternative Names
MARVELD3; MRVLDC3; MARVEL domain-containing protein 3
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human MARVEL domain-containing protein 3 protein (1-189AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
As a component of tight junctions, plays a role in paracellular ion conductivity.
Gene References into Functions
  1. MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. PMID: 24567356
  2. MarvelD3 is transcriptionally downregulated in Snail-induced epithelial-mesenchymal transition during the progression for the pancreatic cancer. PMID: 21763689
  3. marvelD3, occludin, and tricellulin define the tight junction-associated MARVEL protein family PMID: 20164257
  4. MarvelD3 co-localises with occludin at tight junctions in intestinal and corneal epithelial cells. PMID: 20028514
Subcellular Location
Membrane; Multi-pass membrane protein. Cell junction, tight junction.
Database Links

HGNC: 30525

OMIM: 614094

KEGG: hsa:91862

UniGene: Hs.513706

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