MCHR2 Antibody, Biotin conjugated

1. evidence for the involvement of duplications in MCHR2 in alopecia areata pathogenesis in a Central European cohort PMID: 27306922
2. This study provides new insights on the possible influence of MCHR2 and/or MCHR2-AS1 on obesity in psychiatric patients and on the pathophysiology of atypical depression. PMID: 26461262
3. Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2 PMID: 22123324
4. construction of the CHO cell line and the research of MCHR2 molecular characteristics have established a good experimental basis for the further research about the function of MCHR2 gene PMID: 20099459
5. MCH1 and MCH2 receptors were investigated and are different from those in SVK14 cells. PMID: 12127971
6. results of molecular simulations of MCHR2 in the free and hormone-bound forms provide suggestions on the amino acids responsible for the transfer of the structural changes from the agonist binding site to the G-protein coupling domains PMID: 15229878
7. MCHR2 is not a major contributor to polygenic obesity PMID: 17698913
8. MCHR2 positively mediates the regulation of melanin-concentrating hormone during preadipocyte differentiation and is involved in energy balance regulation without affecting preadipocyte proliferation. PMID: 19683862
9. The 10-amino-acid cyclic core of the hMCH neuropeptide with the Arg attached to the N-terminus of the disulfide ring is sufficient for full activation of melanin-concentrating hormone receptor 2. PMID: 11478907

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HGNC: 20867

OMIM: 606111

KEGG: hsa:84539

STRING: 9606.ENSP00000281806

UniGene: Hs.591342