MED27 Antibody

Datasheet

Code	CSB-PA568842
Size	US$297
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Image	Western blot analysis of extracts from HeLa cells, using MED27 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MED27 Polyclonal antibody

Uniprot No.

Q6P2C8

Target Names

MED27

Alternative Names

Cofactor required for Sp1 transcriptional activation subunit 8 (34kD) antibody; Cofactor required for Sp1 transcriptional activation subunit 8 34kDa antibody; Cofactor required for Sp1 transcriptional activation subunit 8 antibody; CRAP 34 antibody; CRAP34 antibody; CRSP 34 antibody; CRSP 8 antibody; CRSP complex subunit 8 antibody; CRSP34 antibody; CRSP8 antibody; MED 27 antibody; Med27 antibody; MED27_HUMAN antibody; Mediator complex subunit 27 antibody; Mediator of RNA polymerase II transcription subunit 27 antibody; MGC11274 antibody; P37 TRAP/SMCC/PC2 subunit antibody; Transcriptional coactivator CRSP34 antibody; TRAP 37 antibody; TRAP37 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from Internal of Human MED27.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene References into Functions

The findings of the present study may aid in the clarification of the function of miR18a, particularly as regards its role in the regulation of Osteosarcoma (OS)cell apoptosis, and indicate that MED27 may be a potential novel therapeutic target in the treatment of OS. PMID: 29693135
MED27 promotes melanoma growth by targeting AKT/MAPK and NF-kappaB/iNOS signaling pathways. PMID: 26797421

Subcellular Location

Nucleus.

Protein Families

Mediator complex subunit 27 family

Database Links

HGNC: 2377

OMIM: 605044

KEGG: hsa:9442

STRING: 9606.ENSP00000292035

UniGene: Hs.374262

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Service

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Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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