MIA2 Antibody

Code CSB-PA056159
Size US$297
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  • Western blot analysis of extracts from HuvEc cells, using MIA2 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MIA2 Polyclonal antibody
Uniprot No.
Target Names
MIA2
Alternative Names
FLJ22404 antibody; Melanoma inhibitory activity 2 antibody; Melanoma inhibitory activity protein 2 antibody; Mia2 antibody; MIA2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human MIA2.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis. Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites.
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein Families
MIA/OTOR family
Tissue Specificity
Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. Isoform 1 is specifically expressed in lung, testis, small intestine, colon, pancreas, kidney, liver and prostate
Database Links

HGNC: 18432

OMIM: 608001

KEGG: hsa:4253

STRING: 9606.ENSP00000280082

UniGene: Hs.287694

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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