MOBP Antibody, Biotin conjugated

Code CSB-PA014701LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MOBP Polyclonal antibody
Uniprot No.
Target Names
MOBP
Alternative Names
MOBP antibody; Myelin-associated oligodendrocyte basic protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Myelin-associated oligodendrocyte basic protein (1-81AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
Gene References into Functions
  1. Mutation in MOBP gene is associated with amyotrophic lateral sclerosis. PMID: 27455348
  2. rs1768208 is associated with corticobasal degeneration. PMID: 26077951
  3. The rs1768208 risk polymorphism in MOBP has prognostic value in behavioral-variant frontotemporal dementia. PMID: 24994843
  4. Genotypes at MOBP and EIF2AK3 confer risk predominantly in APOE epsilon4-positive subjects, with indications of an interaction between APOE and MOBP or EIF2AK3 on Alzheimer's disease risk. PMID: 23116876
  5. MOBP mRNA levels were increased in the DLPFC white matter in patients with a history of substance abuse. PMID: 17964117

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Subcellular Location
Cytoplasm, perinuclear region.
Database Links

HGNC: 7189

OMIM: 600948

KEGG: hsa:4336

UniGene: Hs.121333

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