MOBP Antibody

Code CSB-PA014701LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Hela whole cell lysate
    All lanes: MOBP antibody at 4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 21, 10, 24 kDa
    Observed band size: 21 kDa

  • Immunofluorescence staining of 293 cells with CSB-PA014701LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MOBP Polyclonal antibody
Uniprot No.
Target Names
MOBP
Alternative Names
MOBP antibody; Myelin-associated oligodendrocyte basic protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Myelin-associated oligodendrocyte basic protein (1-81AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MOBP Antibody (Product code: CSB-PA014701LA01HU) is Non-conjugated. For MOBP Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA014701LB01HU MOBP Antibody, HRP conjugated ELISA
FITC CSB-PA014701LC01HU MOBP Antibody, FITC conjugated
Biotin CSB-PA014701LD01HU MOBP Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
Gene References into Functions
  1. Mutation in MOBP gene is associated with amyotrophic lateral sclerosis. PMID: 27455348
  2. rs1768208 is associated with corticobasal degeneration. PMID: 26077951
  3. The rs1768208 risk polymorphism in MOBP has prognostic value in behavioral-variant frontotemporal dementia. PMID: 24994843
  4. Genotypes at MOBP and EIF2AK3 confer risk predominantly in APOE epsilon4-positive subjects, with indications of an interaction between APOE and MOBP or EIF2AK3 on Alzheimer's disease risk. PMID: 23116876
  5. MOBP mRNA levels were increased in the DLPFC white matter in patients with a history of substance abuse. PMID: 17964117

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Subcellular Location
Cytoplasm, perinuclear region.
Database Links

HGNC: 7189

OMIM: 600948

KEGG: hsa:4336

UniGene: Hs.121333

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