MOCS2 Antibody

Datasheet

Code	CSB-PA014706ESR1HU
Size	US$166
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Image	Western blot All lanes: MOCS2 antibody at 1.68 μg/ml Lane 1: A549 whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 21 kDa Observed band size: 21 kDa Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA014706ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA014706ESR1HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA014706ESR1HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MOCS2 Polyclonal antibody

Uniprot No.

O96007

Target Names

MOCS2

Alternative Names

MOCS2 antibody; MCBPE antibody; MOCO1 antibody; Molybdopterin synthase catalytic subunit antibody; EC 2.8.1.12 antibody; MOCO1-B antibody; Molybdenum cofactor synthesis protein 2 large subunit antibody; Molybdenum cofactor synthesis protein 2B antibody; MOCS2B antibody; Molybdopterin-synthase large subunit antibody; MPT synthase large subunit antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Molybdopterin synthase catalytic subunit protein (1-188AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC, IP, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200
IP	1:200-1:2000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunoprecipitation (IP) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.

Gene References into Functions

analysis of sites within MOCS2 where mutations cause molybdenum cofactor deficiency PMID: 12732628
There was undisturbed production of both transcripts, while Western blot analysis demonstrated that MOCS2B, the large subunit, is unstable in the absence of MOCS2A. PMID: 16737835
We reported here an infant with MoCD who presented with hypoxic ischaemic encephalopathy and identified a novel mutation, c.130C>T in cDNA of the MOCS2 gene from the infant. PMID: 17158010

Involvement in disease

Molybdenum cofactor deficiency, complementation group B (MOCODB)

Subcellular Location

Cytoplasm, cytosol.

Protein Families

MoaE family, MOCS2B subfamily

Tissue Specificity

Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes.

Database Links

HGNC: 7193

OMIM: 252160

KEGG: hsa:4338

STRING: 9606.ENSP00000380157

UniGene: Hs.163645

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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