MOGAT2 Antibody, Biotin conjugated

1. MGAT2 is a monoacylglycerol acyltransferase expressed in the small intestine PMID: 12621063
2. MGAT2 functions as a dimeric or tetrameric protein and selectively heterodimerizes with DGAT1 in mammalian cells PMID: 24573674
3. Mogat2(IKO) mice increased energy expenditure although to a lesser degree than Mogat2(-/-) mice and were protected against diet-induced weight gain and associated comorbidities PMID: 24784138
4. The described cell-based assay adds a new methodology for the development and evaluation of MGAT2 inhibitors for the treatment of obesity and type 2 diabetes PMID: 25598079
5. Diacylglycerol acyltransferase-2 and monoacylglycerol acyltransferase-2 are ubiquitinated proteins that are degraded by the 26S proteasome PMID: 27531967
6. The use of 1-oleoyl-glycerol-d5 and (U13)C-TG oil followed by LC/ESI/MS/MS detection of stable-isotopic labeled DAG, TG, or glycerol provides a wide range of applications to study pathophysiological regulation of the monoacylglycerol pathway and MGAT2 activity. PMID: 27665677
7. MGAT2 in the intestine plays an indispensable role in enhancing metabolic efficiency but also raise the possibility that MGAT2 in other tissues may contribute to the regulation of energy metabolism. PMID: 23536640
8. MGAT2 may play an important role in dietary fat absorption PMID: 12576479

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HGNC: 23248

OMIM: 610270

KEGG: hsa:80168

STRING: 9606.ENSP00000198801

UniGene: Hs.288568