MOGAT2

MOGAT2 encodes monoacylglycerol O-acyltransferase 2 (MGAT2), a rate-limiting enzyme in intestinal triglyceride (TG) synthesis. It catalyzes the acylation of monoacylglycerol with acyl-CoA to form diacylglycerol, a core step in dietary fat absorption by enterocytes.
Dysregulation of MOGAT2 is associated with obesity, hyperlipidemia, and type 2 diabetes. Its inhibition reduces intestinal TG uptake, making it a potential target for metabolic disorders. Preclinical small-molecule inhibitors have shown efficacy in lowering plasma TG levels and body weight, though clinical development remains in early phases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MOGAT2 Antibody (CSB-PA663570LA01HU)

Validated Data

Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA663570LA01HU at dilution of 1:100

The following MOGAT2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

MOGAT2 Antibodies

MOGAT2 Proteins

MOGAT2 Antibodies

MOGAT2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA014711GA01HU	MOGAT2 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA663570LA01HU	MOGAT2 Antibody	Human	ELISA, IHC
CSB-PA663570LB01HU	MOGAT2 Antibody, HRP conjugated	Human	ELISA
CSB-PA663570LC01HU	MOGAT2 Antibody, FITC conjugated	Human
CSB-PA663570LD01HU	MOGAT2 Antibody, Biotin conjugated	Human	ELISA

MOGAT2 Proteins

MOGAT2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF663570HU	Recombinant Human 2-acylglycerol O-acyltransferase 2 (MOGAT2)	in vitro E.coli expression system
CSB-YP663570HU1 CSB-EP663570HU1 CSB-BP663570HU1 CSB-MP663570HU1 CSB-EP663570HU1-B	Recombinant Human 2-acylglycerol O-acyltransferase 2 (MOGAT2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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MOGAT2

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