MRPS27 Antibody

Code CSB-PA022313
Size US$297
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  • Western blot analysis of extracts from HeLa cells and HUVEC cells, using MRPS27 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MRPS27 Polyclonal antibody
Uniprot No.
Target Names
MRPS27
Alternative Names
28S ribosomal protein S27 antibody; 28S ribosomal protein S27, mitochondrial antibody; KIAA0264 antibody; Mitochondrial 28S ribosomal protein S27 antibody; mitochondrial antibody; mitochondrial ribosomal protein S27 antibody; MRP-S27 antibody; MRPS27 antibody; RT27_HUMAN antibody; S27mt antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human MRPS27.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth.
Gene References into Functions
  1. we verified for the first time that mitochondrial ribosomal protein S23 expression was upregulated in hepatocellular carcinoma. High mitochondrial ribosomal protein S23 levels can predict poor clinical outcomes in hepatocellular carcinoma, and this protein plays a key role in tumor proliferation. Therefore, mitochondrial ribosomal protein S23 may be a potential therapeutic target for hepatocellular carcinoma. PMID: 28714366
  2. MRPS27 is required for mitochondrial protein synthesis PMID: 22841715
Subcellular Location
Cytoplasm. Mitochondrion.
Protein Families
Mitochondrion-specific ribosomal protein mS27 family
Tissue Specificity
Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level). Ubiquitous.
Database Links

HGNC: 14512

OMIM: 611989

KEGG: hsa:23107

STRING: 9606.ENSP00000261413

UniGene: Hs.482491

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