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| Code | CSB-PA010100PA07me1HU |
| Size | US$319 |
| Uniprot No. | P0C0S5 |
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| Protocols | ELISA Protocol Immunofluorescence (IF) Protocol |
| Immunogen | Peptide sequence around site of Mono-methyl-Lys (7) derived from Human Histone H2A.Z |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA, ICC, IF; Recommended dilution: ICC:1:20-1:200, IF:1:50-1:200 |
| Relevance | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method | Antigen Affinity Purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Histone H2A.Z (H2A/z), H2AFZ, H2AZ |
| Immunogen Species | Human |
| Research Area | Epigenetics and Nuclear Signaling |
| Target Names | H2AFZ |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. |
| Subcellular Location | Nucleus, Chromosome |
| Protein Families | Histone H2A family |
| Database Links |
HGNC: 4741 OMIM: 142763 KEGG: hsa:3015 STRING: 9606.ENSP00000296417 UniGene: Hs.119192 |
| Pathway | Necroptosis |
H2AFZ Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA010100GA01HU | H2AFZ Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA000438 | Acetyl-Histone H2A.Z (Lys7) Antibody | Human,Mouse,Rat | WB,ELISA |
| CSB-PA000456 | Acetyl-Histone H2A.Z (Lys4) Antibody | Human,Mouse,Rat | WB |
| CSB-PA009100 | Acetyl-H2AFZ (K5) Antibody | Human,Mouse,Rat | IHC,ELISA |
| CSB-PA009105 | H2AFZ Antibody | Human,Mouse,Rat | IHC,ELISA |
| CSB-PA011027 | H2AFZ Antibody | Mouse,Rat | WB |
| CSB-PA393326 | Histone H2A.Z Antibody | Human,Mouse,Rat | WB,ELISA |
H2AFZ Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA010100ESR2HU | H2AFZ Antibody | Human | ELISA, IHC |
| CSB-PA010100PA11acHU | Acetyl-H2AFZ (K11) Antibody | Human | ELISA, WB, IF, ChIP |
| CSB-PA010100PA11nacHU | H2AFZ (Ab-11) Antibody | Human | ELISA, IF |
| CSB-PA010100PA07nme1HU | H2AFZ (Ab-7) Antibody | Human | ELISA, IF |
| CSB-PA010100OA04acHU | Acetyl-H2AFZ (K4) Antibody | Human | ELISA, WB, ICC, IF, IP, ChIP |
| CSB-PA010100OA04nacHU | H2AFZ (Ab-4) Antibody | Human, Mouse | ELISA, WB, IHC, IF, IP, ChIP |
| CSB-PA010100OA07acHU | Acetyl-H2AFZ (K7) Antibody | Human | ELISA, WB, ICC, IF, IP, ChIP |
| CSB-PA010100OA07nacHU | H2AFZ (Ab-7) Antibody | Human | ELISA, WB, IHC |
| CSB-PA010100OA04me1HU | Mono-methyl-H2AFZ (K4) Antibody | Human | ELISA, ICC, IF, ChIP |
| CSB-PA010100OA04nme1HU | H2AFZ (Ab-4) Antibody | Human | ELISA, WB, IHC, IF, ChIP |
H2AFZ Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP010100HU CSB-BP010100HU CSB-MP010100HU |
Recombinant Human Histone H2A.Z(H2AFZ) | Yeast Baculovirus Mammalian cell |
| CSB-EP010100HU | Recombinant Human Histone H2A.Z(H2AFZ) | E.coli |
2-hydroxyisobutyryl-HIST1H2BC (K24) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
