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NAA25 Antibody

Datasheet
Code CSB-PA617948ESR1HU
Size US$166
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  • Western Blotting(WB) - NAA25 Antibody

    Western blot
    All lanes: NAA25 antibody at 2.12µg/ml
    Lane 1: Mouse liver tissue
    Lane 2: Mouse kidney tissue
    Lane 3: Hela whole cell lysate
    Lane 4: 293T whole cell lysate
    Lane 5: A549 whole cell lysate
    Lane 6: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 113, 100 kDa
    Observed band size: 113, 100 kDa

  • Immunohistochemistry(IHC) 1- NAA25 Antibody

    Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA617948ESR1HU at dilution of 1:100

  • Immunohistochemistry(IHC) 2- NAA25 Antibody

    Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA617948ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NAA25 Polyclonal antibody
Uniprot No.
Q14CX7
Target Names
NAA25
Alternative Names
C12orf30 antibody; DKFZp667K2112 antibody; FLJ1308 antibody; MDM20 antibody; Mitochondrial distribution and morphology 20 antibody; Mitochondrial distribution and morphology protein 20 antibody; N(alpha)-acetyltransferase 25, NatB auxiliary subunit antibody; N-alpha-acetyltransferase 25, NatB auxiliary subunit antibody; N-terminal acetyltransferase B complex subunit MDM20 antibody; N-terminal acetyltransferase B complex subunit NAA25 antibody; Naa25 antibody; NAA25_HUMAN antibody; NAP1 antibody; NatB complex subunit MDM20 antibody; p120 antibody; TPR repeat-containing protein C12orf30 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human N-alpha-acetyltransferase 25, NatB auxiliary subunit protein (703-972AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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NAA25 Antibodies

NAA25 Proteins

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Target Background

Function
Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp-Glu. May play a role in normal cell-cycle progression.
Gene References into Functions
  1. Mdm20 acts as a novel regulator of Rictor, thereby controlling mTORC2 activity, and leading to the activation of PKCalphaS657 and FoxO1. PMID: 26600389
  2. The human NatB complex composed of Naa20 (NAT3) and Naa25 (MDM20) N-terminally acetylates Met-Glu-, Met-Asp-, Met-Asn- and Met-Gln- N-termini, and is important for the structure and function of actomyosin fibers and for proper cellular migration. PMID: 22814378
  3. The C120rf30 gene maps into a region of extensive linkage disequilibrium including several genes that represent functional candidates of type 1 diabetes-susceptibility. PMID: 20089178
  4. Human N-acetyltransferase complexe NatB consists of human N-acetyltransferase 3 and human MDM20. The hMDM20 knockdown decreased the fraction of cells in G(0)/G(1)-phase and increased the fraction of cells in the sub-G(0)/G(1)-phase. PMID: 18570629
  5. There are associations between juvenile idiopathic arthritis and variants in the TNFAIP3, STAT4, and C12orf30 regions that have previously shown associations with other autoimmune diseases, including rheumatoid arthritis and systemic lupus erythematosus. PMID: 19565500
  6. hMdm20 (C12orf30) is an auxiliary subunit of the human NatB N-terminal acetyltransferase complex while hNat3 (NAT5) is the catalytic subunit. This ribosome associated complex acetylates nascent Met-Asp/Glu- polypeptides. PMID: 18570629

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Subcellular Location
Cytoplasm.
Protein Families
MDM20/NAA25 family
Database Links

HGNC: 25783

OMIM: 612755

KEGG: hsa:80018

STRING: 9606.ENSP00000261745

UniGene: Hs.530941

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