NDUFS7 Antibody

Datasheet

Code	CSB-PA121181
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA121181(NDUFS7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA121181(NDUFS7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O75251

Target Names

NDUFS7

Alternative Names

CI 20 antibody; CI-20kD antibody; Complex I 20kDa subunit antibody; Complex I mitochondrial respiratory chain 20 KD subunit antibody; Complex I-20kD antibody; FLJ45860 antibody; FLJ46880 antibody; MGC120002 antibody; MY017 antibody; NADH coenzyme Q reductase antibody; NADH dehydrogenase (ubiquinone) Fe S protein 7 20kDa (NADH coenzyme Q reductase) antibody; NADH dehydrogenase (ubiquinone) FeS protein 7; 20kDa (NADHcoenzyme Q reductase) antibody; NADH dehydrogenase (ubiquinone) FeS protein7; 20kDa (NADHcoenzyme Q reductase) antibody; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7; mitochondrial antibody; NADH-ubiquinone oxidoreductase 20 kDa subunit antibody; NADH:ubiquinone oxidoreductase PSST subunit antibody; NADHcoenzyme Q reductase antibody; Ndufs7 antibody; NDUS7_HUMAN antibody; PSST antibody; PSST subunit antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Fusion protein of Human NDUFS7

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.

Gene References into Functions

However, similar to another family member, RdmB, it catalyzes the introduction of a hydroxyl group, in the case of NDUFAF5, into Arg-73 in the NDUFS7 subunit of human complex I PMID: 27226634
no active role of NDUFS7 gene in schizophrenia, was found. PMID: 22935918
Observational study of gene-disease association. (HuGE Navigator) PMID: 20877624
A patient with Leigh syndrome (LS), born to consanguineous parents, with severe complex I defect and a novel mutation in the NDUFS7 gene subunit. PMID: 17275378
Intronic NDUFS7 gene mutation is associated with activation of a cryptic exon and impaired assembly of mitochondrial complex I in a patient with Leigh syndrome PMID: 17604671
Both the amount and intrinsic activity of complex I are decreased in inherited complex I deficiency, ehich can be increased by Trolox. PMID: 18435906
Observational study of gene-disease association. (HuGE Navigator) PMID: 17601350
Observational study of gene-disease association. (HuGE Navigator) PMID: 18977241

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Involvement in disease

Leigh syndrome (LS); Mitochondrial complex I deficiency (MT-C1D)

Subcellular Location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Protein Families

Complex I 20 kDa subunit family

Database Links

HGNC: 7714

OMIM: 252010

KEGG: hsa:374291

STRING: 9606.ENSP00000233627

UniGene: Hs.211914

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

The Overview of Organelles Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Oxidative Phosphorylation

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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