NDUFS8 Antibody

Code CSB-PA015667LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Rat brain tissue
    All lanes: NDUFS8 antibody at 2.7μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 24 kDa
    Observed band size: 24 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NDUFS8 Polyclonal antibody
Uniprot No.
Target Names
NDUFS8
Alternative Names
CI 23kD antibody; CI-23kD antibody; Complex I 23kD antibody; Complex I-23kD antibody; EC 1.6.5.3 antibody; EC 1.6.99.3 antibody; Human mitochondrial NADH dehydrogenase ubiquinone Fe S protein 8 antibody; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8; mitochondrial antibody; NADH ubiquinone oxidoreductase 23 kDa subunit antibody; NADH-ubiquinone oxidoreductase 23 kDa subunit antibody; NDUFS8 antibody; NDUS8_HUMAN antibody; TYKY antibody; TYKY subunit antibody; Ubiquinoneiron sulfur protein 8; mitochondrial precursor antibody
Raised in
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial protein (35-210AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NDUFS8 Antibody (Product code: CSB-PA015667LA01HU) is Non-conjugated. For NDUFS8 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA015667LB01HU NDUFS8 Antibody, HRP conjugated ELISA
FITC CSB-PA015667LC01HU NDUFS8 Antibody, FITC conjugated
Biotin CSB-PA015667LD01HU NDUFS8 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Gene References into Functions
  1. Results show that NDUFS8 protein and mRNA levels are up-regulated in lung neoplasm and correlate with poor overall survival. PMID: 27516145
  2. 2 new mutations (P85L upstream from the 2 cysteine motifs that coordinate the two [4Fe-4S] clusters which generate the complex I N2 clusters, & R138H between them)suggest that this subunit is essential for either the assembly or stability of complex I. PMID: 15159508
Involvement in disease
Leigh syndrome (LS)
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families
Complex I 23 kDa subunit family
Tissue Specificity
Expressed in all tissues with the highest level in heart and skeletal muscle and the lowest level in lung.
Database Links

HGNC: 7715

OMIM: 256000

KEGG: hsa:4728

STRING: 9606.ENSP00000315774

UniGene: Hs.90443

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