NINL Antibody

1. Upon UVC radiation, Nlp interacts with XPA and ERCC1, and enhances their association PMID: 26805762
2. these data support a model where CC2D2A associates with NINL to provide a docking point for cilia-directed cargo vesicles, suggesting a mechanism by which transition zone proteins can control the protein content of the ciliary compartment. PMID: 26485645
3. Overexpression of ninein and the ninein-like protein NIP induces fragmentation of the Golgi and causes lysosomes to disperse toward the cell periphery. PMID: 16254247
4. Breast cancer patients with high expression of Nlp were likely resistant to the treatment of paclitaxel. PMID: 22353935
5. This review summarises our current knowledge of physiological roles of Nlp, with an emphasis on its potentials in tumourigenesis. PMID: 21505454
6. findings demonstrate that Cdc2/cyclin B1 is a key regulator in maintaining appropriate degradation and subcellular localization of Nlp, providing novel insights into understanding on the role of Cdc2/cyclin B1 in mitotic progression PMID: 20890132
7. regulation of Nlp by Aurora B is critical for the completion of cytokinesis, providing novel insights into understanding the machinery of cell cycle progression. PMID: 20864540
8. Nlp abnormalities may contribute to genomic instability and tumorigenesis and might serve as a potential biomarker for clinical diagnosis and as a therapeutic target. PMID: 20093778
9. results indicate that ninein-like protein expression is cell cycle-dependent and regulated by anaphase-promoting cyclosome complex-mediated protein degradation PMID: 17403670
10. Overexpression of Nlp in ovarian tumors raises the possibility that Nlp may play a role in ovarian carcinogenesis. PMID: 18538832
11. Nlp(isoB)interacts with USH2A and lebercilin. PMID: 18826961
12. BRCA1 interaction of Nlp might be required for the successful mitotic progression, and abnormalities of Nlp lead to genomic instability. PMID: 19509300
13. Nlp overexpression might contribute to the development of head and neck squamous cell carcinoma PMID: 19724857

Show More

Hide All

HGNC: 29163

OMIM: 609580

KEGG: hsa:22981

STRING: 9606.ENSP00000278886

UniGene: Hs.631508