NP Antibody

Datasheet

Code	CSB-PA325769LA01IIM
Size	US$166
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Image	Western Blot Positive WB detected in Recombinant protein All lanes: NP antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 71 kDa Observed band size: 71 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Influenza A virus NP Polyclonal antibody

Uniprot No.

P15682

Target Names

Alternative Names

NP antibody; Nucleoprotein antibody; Nucleocapsid protein antibody; Protein N antibody

Raised in

Rabbit

Species Reactivity

Influenza A virus

Immunogen

Recombinant Influenza A virus Nucleoprotein protein (1-498AA)

Immunogen Species

Influenza A virus

Conjugate

Non-conjugated

The NP Antibody (Product code: CSB-PA325769LA01IIM) is Non-conjugated. For NP Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA325769LB01IIM	NP Antibody, HRP conjugated	ELISA
FITC	CSB-PA325769LC01IIM	NP Antibody, FITC conjugated
Biotin	CSB-PA325769LD01IIM	NP Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.

Subcellular Location

Virion. Host nucleus.

Protein Families

Influenza viruses nucleoprotein family

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