NR6A1 Antibody

1. GCNF acts as a transcriptional repressor in the regulation of OCT4 gene expression through cooperative interaction with three NR binding elements in pluripotent NCCIT cells. PMID: 29057499
2. the genes, and up-regulated 64% in undifferentiated hES cells. In addition, GCNF also showed a regulatory gene pattern that is different from RA treatment during hES cell differentiation PMID: 26769970
3. Findings show a role for Gcnf as a regulator of iPS cell pluripotency gene expression. It also demonstrates that reactivation of the Gcnf gene may serve as a marker to distinguish completely reprogrammed iPS cells from incompletely pluripotent cells. PMID: 23495137
4. Our results show that cellular levels of NR6A1 are correlated with disease progression in prostate cancer. PMID: 23532770
5. These experiments confirmed that NR6A1 works as a regulator for hypocretin transcription. PMID: 21056546
6. RTR mRNA was expressed in the human placental choriocarcinoma cell lines BeWo, JAR, and JEG-3. PMID: 11969338
7. characterization of a novel nuclear protein, referred to as RAP80, that interacts with the retinoid-related testis-associated receptor PMID: 12080054
8. down-regulation of CREMtau-mediated gene expression by GCNF PMID: 15456763

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HGNC: 7985

OMIM: 602778

KEGG: hsa:2649

STRING: 9606.ENSP00000420267

UniGene: Hs.20131