NRXN1 Antibody

Code CSB-PA347832LA01HU
Size US$166
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  • Immunofluorescent analysis of HepG2 cells using CSB-PA347832LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Western Blot
    Positive WB detected in: Mouse heart tissue, Mouse kidney tissue
    All lanes: NRXN1 antibody at 2μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 47, 51, 162, 165, 170, 16 kDa
    Observed band size: 47 kDa

  • Western Blot
    Positive WB detected in: MCF-7 whole cell lysate, Mouse Liver tissue, Mouse Kidney tissue
    All lanes: NRXN1 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 47 kDa
    Observed band size: 47 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NRXN1 Polyclonal antibody
Uniprot No.
Target Names
NRXN1
Alternative Names
NRXN1 antibody; Neurexin-1-beta antibody; Neurexin I-beta antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Neurexin-1-beta protein (184-363AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The NRXN1 Antibody (Product code: CSB-PA347832LA01HU) is Non-conjugated. For NRXN1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA347832LB01HU NRXN1 Antibody, HRP conjugated ELISA
FITC CSB-PA347832LC01HU NRXN1 Antibody, FITC conjugated
Biotin CSB-PA347832LD01HU NRXN1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:2000-1:5000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The NRXN1 polyclonal antibody is raised in the rabbit immunized with the recombinant human neurexin-1-beta protein (184-363aa). It exists as an unconjugated IgG isoform. And it is purified by protein G and reaches above 95% in purity. This NRXN1 antibody only reacts with human and mouse NRXN1 proteins. It has been subjected to quality control in three applications, including ELISA, WB, and IF.

Its target protein NRXN1 mainly mediates synapse formation and regulates the communication between neurons in the brain. Additionally, NRXN1 has been implicated in several neuropsychiatric disorders, including autism spectrum disorder (ASD), schizophrenia, and intellectual disability.

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 Customer Reviews
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Applications : Immunocytochemistry

Sample type: cell

Review: Immunocytochemistry using a commercial anti-NRXN1α antibody. Serum and CSF were used from a schizophrenia patient 1, and serum was used from healthy controls.

By Anonymous

Target Background

Function
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis.
Subcellular Location
Cell junction, synapse, presynaptic cell membrane; Single-pass type I membrane protein.
Protein Families
Neurexin family
Database Links

HGNC: 8008

OMIM: 600565

KEGG: hsa:9378

UniGene: Hs.637685

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