NT5C1A Antibody, FITC conjugated

Datasheet

Code	CSB-PA866304YC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) NT5C1A Polyclonal antibody

Uniprot No.

Q9BXI3

Target Names

NT5C1A

Alternative Names

5' nucleotidase cytosolic IA antibody; 5NT1A_HUMAN antibody; AMP specific 5' NT antibody; CN I antibody; CN IA antibody; cN-I antibody; cN-IA antibody; CN1 antibody; cN1A antibody; cNI antibody; cNIA antibody; Cytosolic 5' nucleotidase 1A antibody; Cytosolic 5' nucleotidase IA antibody; Cytosolic 5' nucleotidase type 1A antibody; Cytosolic 5''-nucleotidase 1A antibody; Cytosolic 5''-nucleotidase IA antibody; MGC119199 antibody; MGC119201 antibody; NT5C1A antibody; nucleotidase; 5-prime; cytosolic; IA antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cytosolic 5\'-nucleotidase 1A protein (1-368AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.

Gene References into Functions

Individual missense changes in NT5C1A showed considerable variation in response to the different nucleoside analogs tested. PMID: 26906009
seropositivity to the NT5c1A antibody is associated with greater motor and functional disability in sporadic inclusion body myositis PMID: 25857661
Anti-NT5C1A is a common target of circulating autoantibodies in autoimmune diseases. PMID: 25892010
NT5C1A suppression promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle PMID: 21873433
overexpression of 5'-nucleotidase inhibits Natural Killer cell cytotoxicity to ameliorate rejection after xenotransplantation PMID: 15888028
deoxycytidine kinase, deoxyguanosine kinase, and cytosolic 5'-nucleotidase I are regulated in a cell cycle-dependent manner in MOLT-4 cells PMID: 17065091
There was no correlation between expression of cN-I and fiber type. PMID: 19352542

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Subcellular Location

Cytoplasm.

Protein Families

5'-nucleotidase type 3 family

Tissue Specificity

Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.

Database Links

HGNC: 17819

OMIM: 610525

KEGG: hsa:84618

STRING: 9606.ENSP00000235628

UniGene: Hs.307006

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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