NXN Antibody

Datasheet

Code	CSB-PA016224HA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, A549 whole cell lysate All lanes: NXN antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 49, 21, 37 kDa Observed band size: 49 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) NXN Polyclonal antibody

Uniprot No.

Q6DKJ4

Target Names

NXN

Alternative Names

FLJ12614 antibody; NRX antibody; nucleoredoxin 1 antibody; Nucleoredoxin antibody; Nxn antibody; NXN_HUMAN antibody; OTTHUMP00000115356 antibody; TRG 4 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Nucleoredoxin protein (155-435AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The NXN Antibody (Product code: CSB-PA016224HA01HU) is Non-conjugated. For NXN Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA016224HB01HU	NXN Antibody, HRP conjugated	ELISA
FITC	CSB-PA016224HC01HU	NXN Antibody, FITC conjugated
Biotin	CSB-PA016224HD01HU	NXN Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).

Gene References into Functions

identified nucleoredoxin as an interaction partner of Sec63; characterized this interaction; Sec63 is linked to the Wnt signaling pathways and this interaction may be the reason why mutations in SEC63 can lead to polycystic liver disease PMID: 21251912
Nucleoredoxin is a novel thioredoxin family member involved in cell growth and differentiation [review] PMID: 17567240

Subcellular Location

Cytoplasm, cytosol. Nucleus.

Protein Families

Nucleoredoxin family

Database Links

HGNC: 18008

OMIM: 612895

KEGG: hsa:64359

STRING: 9606.ENSP00000337443

UniGene: Hs.527989

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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