Name: OPTC Antibody, HRP conjugated
Brand: CUSABIO
SKU: CSB-PA016362LB01HU

Product Details

Full Product Name	Rabbit anti-Homo sapiens (Human) OPTC Polyclonal antibody
Uniprot No.	Q9UBM4
Target Names	OPTC
Alternative Names	Oculoglycan antibody; OPT antibody; OPT_HUMAN antibody; OPTC antibody; Opticin antibody
Raised in	Rabbit
Species Reactivity	Human
Immunogen	Recombinant Human Opticin protein (20-332AA)
Immunogen Species	Homo sapiens (Human)
Conjugate	HRP
Clonality	Polyclonal
Isotype	IgG
Purification Method	Antigen Affinity Purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function	Binds collagen fibrils.
Gene References into Functions	opticin binds to collagen and thereby competitively inhibits endothelial cell interactions with collagen via alpha(1)beta(1) and alpha(2)beta(1) integrins, thereby preventing the strong adhesion that is required for proangiogenic signaling via these integrins. PMID: 22669977 VEGF and hypoxia could decrease opticin protein levels in the human retinal pigment epithelium secretome, and that opticin may be an enzymatic substrate for MMP-2. PMID: 22534113 localization in the human eye and genetic screen of opticin PMID: 12019215 OPTC is a candidate gene for primary open-angle glaucoma PMID: 17359525 OPTC and EPYC are unlikely to play a major role in high myopia. PMID: 19844586 Show More Hide All
Subcellular Location	Secreted, extracellular space, extracellular matrix
Protein Families	Small leucine-rich proteoglycan (SLRP) family, SLRP class III subfamily
Tissue Specificity	Retina, iris, ligament, skin and fetal liver.
Database Links	HGNC: 8158 OMIM: 605127 KEGG: hsa:26254 STRING: 9606.ENSP00000356191 UniGene: Hs.632468

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Check Code：

Code	CSB-PA016362LB01HU
Size	US$299
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OPTC Antibody, HRP conjugated