OSGIN1 Antibody

Code CSB-PA017258GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
Alternative Names
OSGIN1 antibody; BDGI antibody; OKL38 antibody; Oxidative stress-induced growth inhibitor 1 antibody; Bone marrow stromal cell-derived growth inhibitor antibody; BMSC-derived growth inhibitor antibody; Ovary antibody; kidney and liver protein 38 antibody; huOKL38 antibody; Pregnancy-induced growth inhibitor OKL38 antibody
Raised in
Species Reactivity
Human OSGIN1
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen Affinity purified
It differs from different batches. Please contact us to confirm it.
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Regulates the differentiation and proliferation through the regulation of cell death.
Gene References into Functions
  1. The results support the concept that smoking-induced upregulation of OSGIN1 is one link between smoking-induced stress and enhanced-autophagy in the human airway epithelium. PMID: 28548877
  2. miR-320a has a role in modulating the induction of HO-1, GCLM and OKL38 by oxidized phospholipids in endothelial cells PMID: 24786516
  3. Identify OSGIN1 as a tumor suppressor that is down-regulated or altered in human hepatocellular carcinoma. PMID: 24417816
  4. Data suggest that OKL38 regulates mitochondria morphology and functions during apoptosis together with p53. PMID: 22912861
  5. Expression in cultured tumor cells resulted in growth inhibition and cell death. PMID: 14570898
  6. BDGI (Bone marrow stromal cell-derived growth inhibitor) inhibits growth and migration of breast cancer cells via induction of cell cycle arrest and apoptosis [BDGI] PMID: 15569677
  7. The 5'UTRs of OKL38 might play an important role in downregulation of its protein and the absence of OKL38 could lead to the development or progression of hepatocellular carcinoma. PMID: 16924236
  8. identify OKL38 as a novel p53 target gene that is regulated by Peptidylarginine deiminase 4 and plays a role in apoptosis PMID: 18499678

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Protein Families
OKL38 family
Tissue Specificity
Ubiquitous. Highest expression in the ovary, testis, kidney, skeletal muscle and liver. Weakly expressed in spleen, heart, kidney, and pancreas. Highly expressed in tumor cells (at protein level).
Database Links

HGNC: 30093

OMIM: 607975

KEGG: hsa:29948

UniGene: Hs.128055

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