OSTN Antibody, FITC conjugated

1. The circulating concentration of musclin was significantly increased in type 2 diabetes mellitus patients. Results suggest that musclin has a strong relationship with insulin resistance in type 2 diabetes mellitus. PMID: 28185530
2. findings suggest that, in response to sensory input, OSTN regulates features of neuronal structure and function that are unique to primates PMID: 27830782
3. osteocrin represents a novel, unique vitamin D-regulated bone-specific protein that appears to act as a soluble osteoblast regulator PMID: 14523025
4. Foxo1 downregulates musclin mRNA expression both in vitro and in vivo, which should explain insulin-mediated upregulation of this gene in muscle cells. PMID: 17950246
5. Ostn is a naturally occurring ligand of the NPR-C clearance receptor and may act to locally modulate the actions of the natriuretic system in bone by blocking the clearance action of NPR-C, thus locally elevating levels of C-type natriuretic peptide. PMID: 17951249
6. Observational study of gene-disease association. (HuGE Navigator) PMID: 19453261

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HGNC: 29961

OMIM: 610280

KEGG: hsa:344901

STRING: 9606.ENSP00000342356

UniGene: Hs.526794