PACSIN2 Antibody

Code CSB-PA017374GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. Q9UNF0
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Human PACSIN2
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB
Storage Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity Purified
Isotype IgG
Alias protein kinase C and casein kinase substrate in neurons 2;PACSIN2;SDPII ;
Immunogen Species Homo sapiens (Human)
Target Names PACSIN2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
HGNC 8571
RGD 69411
MGI 1345153
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Function Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
Subcellular Location Cytoplasm, Cytoplasm, cytoskeleton, Cytoplasmic vesicle membrane, Peripheral membrane protein, Cytoplasmic side, Early endosome, Recycling endosome membrane, Cell projection, ruffle membrane, Peripheral membrane protein, Cytoplasmic side, Cell membrane, Peripheral membrane protein, Cytoplasmic side, Cell projection, Membrane, caveola
Protein Families PACSIN family
Tissue Specificity Widely expressed.
Database Links

HGNC: 8571

OMIM: 604960

KEGG: hsa:11252

STRING: 9606.ENSP00000263246

UniGene: Hs.162877

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