PDE4DIP Antibody

Code CSB-PA716571ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA716571ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA716571ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PDE4DIP Polyclonal antibody
Uniprot No.
Target Names
PDE4DIP
Alternative Names
Cardiomyopathy associated protein 2 antibody; Cardiomyopathy-associated protein 2 antibody; CMYA2 antibody; MMGL antibody; MYOME_HUMAN antibody; Myomegalin antibody; Pde4dip antibody; Phosphodiesterase 4D interacting protein antibody; Phosphodiesterase 4D-interacting protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Myomegalin protein (1-310AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.; Participates in microtubule dynamics, promoting microtubule assembly. Depending upon the cell context, may act at the level of the Golgi apparatus or that of the centrosome. In complex with AKAP9, recruits CAMSAP2 to the Golgi apparatus and tethers non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. In complex with AKAP9, EB1/MAPRE1 and CDK5RAP2, contributes to microtubules nucleation and extension from the centrosome to the cell periphery, a crucial process for directed cell migration, mitotic spindle orientation and cell-cycle progression.
Involvement in disease
A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP-PDGFRB fusion protein.
Subcellular Location
Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.; [Isoform 13]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Golgi apparatus.
Tissue Specificity
Highly expressed in adult and fetal heart, in skeletal muscle and, to a lower extent, in brain and placenta.
Database Links

HGNC: 15580

OMIM: 608117

KEGG: hsa:653513

STRING: 9606.ENSP00000358363

UniGene: Hs.584841

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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