PGLYRP2 Antibody, Biotin conjugated

Code CSB-PA846684LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PGLYRP2 Polyclonal antibody
Uniprot No.
Target Names
PGLYRP2
Alternative Names
PGLYRP2 antibody; PGLYRPL antibody; PGRPL antibody; UNQ3103/PRO10102 antibody; N-acetylmuramoyl-L-alanine amidase antibody; EC 3.5.1.28 antibody; Peptidoglycan recognition protein 2 antibody; Peptidoglycan recognition protein long antibody; PGRP-L antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human N-acetylmuramoyl-L-alanine amidase protein (22-576AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
Gene References into Functions
  1. This study demonistrated that PGLYRP2 single-nucleotide polymorphisms is risk of Parkinson's disease. PMID: 24838182
  2. Various types of human blood cells were tested for expression of the Tag7/PGRP-SA and TagL/PGRP-L proteins, which belong to the family of proteins possessing the lysozyme-like peptidoglycan recognition protein (PGRP) domain PMID: 12669421
  3. Serum N-acetylmuramoyl-l-alanine amidaseand liver PGLYRP2 are the same protein encoded by the pglyrp2 gene. PMID: 16054449
  4. PGLYRP2 may function in the skin and the eyes as an inducible scavenger of proinflammatory peptidoglycan. PMID: 16239516
  5. pglyrp2 expression in skin and liver is important for systemic and local innate immune responses to bacterial infections PMID: 16714290

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Subcellular Location
Secreted. Membrane.
Protein Families
N-acetylmuramoyl-L-alanine amidase 2 family
Tissue Specificity
Strongly expressed in liver and fetal liver, and secreted into serum. Expressed to a much lesser extent in transverse colon, lymph nodes, heart, thymus, pancreas, descending colon, stomach and testis. Isoform 2 is not detected in the liver or serum.
Database Links

HGNC: 30013

OMIM: 608199

KEGG: hsa:114770

STRING: 9606.ENSP00000345968

UniGene: Hs.282244

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