PHF11 Antibody

Code CSB-PA017900GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PHF11
Alternative Names
APY antibody; BCAP antibody; BRCA1 C-terminus-associated protein antibody; IgE responsiveness (atopic) antibody; IGEL antibody; IGER antibody; IGHER antibody; NY REN 34 antigen antibody; NY-REN-34 antibody; NYREN34 antibody; PHD finger protein 11 antibody; Phf11 antibody; PHF11_HUMAN antibody; Renal carcinoma antigen NY-REN-34 antibody; RP11-185C18.3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human PHF11
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Positive regulator of Th1-type cytokine gene expression.
Gene References into Functions
  1. data suggest that BCAP exists as two isoforms with subtly different roles in inhibition of ciliogenesis. Both are required to prevent ciliogenesis and one additionally controls cilium length after ciliogenesis has completed. PMID: 28775150
  2. contributes to T-cell activation and viability PMID: 20421878
  3. the single nucleotide polymorphism rs1046295 of PHF11 modulates allele-specific binding by the octamer-binding transcription factor 1 PMID: 21320718
  4. PHF11 (PHD finger protein 11) is not a major candidate gene for asthma or eczema in Chinese children PMID: 20717939
  5. We were unable to confirm associations of single nucleotide polymorphisms of the positional candidates DPP10 and PHF11 with wheeze. Significant associations with reported and examined eczema were only observed for DPP10. PMID: 20085599
  6. rs1046295 and rs16659 associated with asthma susceptibility in a Han Chinese population PMID: 19672052
  7. Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. PMID: 12754510
  8. Results provide some further support for the role of genetic variation in PHF11 in asthma susceptibility. PMID: 17702965
  9. PHF11 is a regulator of T(H)1-type cytokine gene expression PMID: 18405956
  10. PHF11 is unlikely to contain polymorphic loci that have a major impact on asthma susceptibility in two independent populations. PMID: 19386584

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Subcellular Location
Nucleus.
Tissue Specificity
Highly expressed in T and B-cells, as well as natural killer and mature dendritic cells. Expressed at higher levels in Th1 as compared to Th2 cells. Expressed at low levels in all normal tissues tested, including lung, testis, small intestine, breast, liv
Database Links

HGNC: 17024

OMIM: 147050

KEGG: hsa:51131

STRING: 9606.ENSP00000367570

UniGene: Hs.369039

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