PHKB Antibody

Code CSB-PA941946
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA941946(PHKB Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA941946(PHKB Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
Alternative Names
DKFZp781E15103 antibody; FLJ41698 antibody; KPBB_HUMAN antibody; PHKB antibody; Phosphorylase b kinase regulatory subunit beta antibody; Phosphorylase kinase B antibody; Phosphorylase kinase beta polypeptide antibody; Phosphorylase kinase beta subunit antibody; Phosphorylase kinase subunit beta antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human PHKB
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:20-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
Gene References into Functions
  1. PHKb affects colorectal cancer cell growth and represents a novel prognostic biomarker. PMID: 28275865
  2. Analysis showed that the glycogen phosphorylase kinase beta-subunit (PHKB) interacted with the C-terminal region of KIAA1199 protein. PMID: 25051373
Involvement in disease
Glycogen storage disease 9B (GSD9B)
Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein Families
Phosphorylase b kinase regulatory chain family
Database Links

HGNC: 8927

OMIM: 172490

KEGG: hsa:5257

STRING: 9606.ENSP00000313504

UniGene: Hs.78060

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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