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PIGK Antibody, HRP conjugated

Datasheet
Code CSB-PA842143LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PIGK Polyclonal antibody
Uniprot No.
Q92643
Target Names
PIGK
Alternative Names
PIGK antibody; GPI8 antibody; GPI-anchor transamidase antibody; GPI transamidase antibody; EC 3.-.-.- antibody; GPI8 homolog antibody; hGPI8 antibody; Phosphatidylinositol-glycan biosynthesis class K protein antibody; PIG-K antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human GPI-anchor transamidase protein (91-293AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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PIGK Proteins

Customer Reviews and Q&A

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Target Background

Function
Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.
Gene References into Functions
  1. Report firstly demonstrated that inadequate protein-glycosylphosphatidylinositol anchoring caused by suppression of PIGK might affect the expression or function of some glycosylphosphatidylinositol-anchored proteins associated with tyrosinase activity. PMID: 27919619
  2. Our results demonstrate, for the first time, a link between the SNP 1048575 and low PIGK expression in CRC/HCC patients and also suggest a possible association between altered PIGK expression and disease susceptibility. PMID: 22824918
  3. GPI8 and PIG-T form a functionally important intermolecular disulfide bridge PMID: 12582175
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein Families
Peptidase C13 family
Database Links

HGNC: 8965

OMIM: 605087

KEGG: hsa:10026

STRING: 9606.ENSP00000359848

UniGene: Hs.178305

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